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Exploring the potential of microbiota transplantation as a novel approach for treating infectious and inflammatory diseases.

Ishan Tiwari
Page No.1-24


Fecal microbiota transplantation (FMT) is a promising new approach for treating various infectious and inflammatory diseases by restoring a healthy gut microbiome. FMT involves transferring fecal material from a healthy donor into the gastrointestinal tract of a recipient. This book chapter explores the current research on FMT as a treatment for Clostridium difficile infection, inflammatory bowel disease, metabolic syndrome, autoimmune diseases, neurological disorders, and liver disorders. FMT has shown high cure rates for C. difficile infection and has been approved by regulatory agencies for this indication. However, challenges remain in developing FMT as a therapeutic approach for other diseases, including standardization of donor screening and faecal material preparation, regulatory approval, and the need for trained healthcare professionals and infrastructure for FMT administration. Despite these challenges, FMT holds promising potential as a novel and effective treatment approach for a wide range of diseases. This chapter provides an overview of the current state of FMT research and highlights the need for further investigation and development of this innovative therapeutic approach. With continued research and collaboration between researchers, clinicians, and regulators, FMT has the potential to revolutionize the treatment of infectious and inflammatory diseases.
Keywords: microbiome, transplant, gut, bacteria, donor, regulation

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