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Thivayta Shanmugam1, Shaamini Selvapaandian1, Thashwina N.G. Punithan1, Nur Atiqah binti Mohd Yusoff1,Nor Elianis binti Norkhairani1,Kaveeyarasi Kumaravel1, Venkataramanan.S1,kavitha.Kannan2,Purushothaman Ayyakkannu3
page No. 46-53


Staphylococcus aureus represent as a gram-positive bacterium which causes a broad range of clinical infections. Infection occurs due to this bacterium is prevalent in both hospitals as well as in the community. Because of the growth of multi-drug resistant bacteria such as MRSA (Methicillin- Resistant Staphylococcus aureus), the treatments are difficult to discover. S.aureus generally not initiate infection on healthy skin unless these bacteria are permitted to reach the internal tissues or bloodstream, which can cause a number of potentially dangerous infections. Staphylococcus aureus has been identified as a significant pathogen. Despite the antibiotic therapy, staphylococcal infections are common in hospitalized patients, and it can be fatal. It is the leading cause of disease and mortality in hospital environment. Its potential to cause disease is enhanced by virulence factors or drug resistance, as evidenced by the emergence of methicillin-resistant staphylococcus aureus (MRSA). Methicillin-resistant Staphylococcus aureus (MRSA) has begun as a serious nosocomial infection in many hospitals throughout the world. In hospitals, the most common sources of s.aureus would be septic lesions and patient and staff carriage sites. Infection is frequently preceded by carriage. This organism which lives as a commensal and has been transmitted in both healthcare and community settings is also a prominent source of bacteremia, skin and soft tissue infections and endocarditis.
Key words: Methicillin-Resistant Staphylococcus aureus (MRSA), nosocomial infection, antibiotic therapy, bacteremia.


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